EU Extends Indication of Bosentan to Pulmonary Arterial … DG News - 10 hours ago … for the treatment of patients with mildly symptomatic pulmonary arterial hypertension (PAH World Health Organization [WHO] functional class [FC] II). …

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Endothelin Antagonist Trial in Mildly Symptomatic Pulmonary … Medscape (subscription) - Jul 31, 2008 Pulmonary arterial hypertension (PAH) is characterized by progressive pulmonary arterial vasoconstriction and remodeling, leading to a marked rise in …

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